Download Approach to Internal Medicine: A Resource Book for Clinical by David Hui, Alexander A. Leung, Raj Padwal PDF

By David Hui, Alexander A. Leung, Raj Padwal

ISBN-10: 331911820X

ISBN-13: 9783319118208

ISBN-10: 3319118218

ISBN-13: 9783319118215

This totally up to date 4th version of presents an built-in symptom- and issue-based method with quick access to excessive yield scientific info. for every subject, conscientiously equipped sections on varied diagnoses, investigations, and coverings are designed to facilitate sufferer care and exam training. quite a few medical pearls and comparability tables are supplied to aid improve studying, and overseas devices (US and metric) are used to facilitate program in daily medical practice.

The ebook covers many hugely very important, hardly mentioned issues in drugs (e.g., smoking cessation, weight problems, transfusion reactions, needle stick accidents, code prestige dialogue, interpretation of gram stain, palliative care), and new chapters on end-of-life care and melancholy were additional. The fourth variation contains many reader-friendly advancements akin to larger formatting, intuitive ordering of chapters, and incorporation of the latest guidance for every subject. Approach to inner medication continues to function an important reference for each clinical pupil, resident, fellow, working towards healthcare professional, nurse, and health practitioner assistant.

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Consider only if hemodynamically unstable or life-threatening pulmonary embolism. 5 million IU over 2 h. Unfractionated heparin may be used concurrently SURGICAL—embolectomy. Consider if thrombolysis failed or contraindicated or if hemodynamically unstable IVC FILTER—if anticoagulation contraindicated TREATMENT ISSUES CONTRAINDICATIONS TO THROMBOLYTIC THERAPY · ABSOLUTE CONTRAINDICATIONS—history of hemorrhagic stroke or stroke of unknown origin, ischemic stroke in previous 3 months, malignant intracranial neoplasm, suspected aortic dissection, active bleeding, major trauma in previous 2 months, intracranial surgery or head injury within 3 weeks · RELATIVE CONTRAINDICATIONS—TIA within 6 months, oral anticoagulation, pregnancy or within 1 week postpartum, non-compressible puncture sites, traumatic/prolonged (>10 min) CPR, uncontrolled hypertension (SBP >185 mmHg, DBP >110 mmHg), recent bleeding (<2–4 weeks), current use of anticoagulants, advanced liver disease, infective endocarditis, active peptic ulcer, thrombocytopenia ANTICOAGULATION DURATION · · · · FIRST PULMONARY EMBOLISM WITH REVERSIBLE OR TIME-LIMITED RISK FACTOR—anticoagulation for at least 3 months UNPROVOKED PE—at least 3 months of treatment.

Urgent interventional bronchoscopy (cold saline, topical epinephrine, cautery, airway blocker, double lumen endotracheal tube). Angiographic arterial embolization. ]. If <3 cm, 20–50% malignant. If ≥3 cm, 50% malignant TIMING—if malignant, usually able to detect an increase in size of SPN between 30 days and 2 years. Unlikely to be malignant if significant change in <30 days or no change in 2 years CALCIFICATION CLUES · MALIGNANCY —eccentric calcification or noncalcified · TUBERCULOSIS OR HISTOPLASMOSIS—central/ complete calcification · BENIGN HAMARTOMA—popcorn calcification · · MANAGEMENT TREAT UNDERLYING CAUSE —if low probability, observation with serial CT scans.

5 mg SC daily (50– 100 kg), or 10 mg SC daily (>100 kg). Start warfarin 5 mg PO daily within 48 h and continue heparin/LMWH/fondaparinux for at least 5 days and until INR is between 2 and 3 for at least 48 h. Factor Xa inhibitors (rivaroxaban, apixaban) and direct thrombin inhibitors (dabigatran) not recommended for initial treatment of hemodynamically unstable PE; may consider in stable patients MANAGEMENT CONT’D under supervision of physician familiar with novel anticoagulant therapy THROMBOLYTICS—controversial as increased risk of intracranial bleed and multiple contraindications (see below).

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Approach to Internal Medicine: A Resource Book for Clinical Practice by David Hui, Alexander A. Leung, Raj Padwal


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