Download Annual Review of Gerontology and Geriatrics, Volume 3, 1982: by Carl Eisdorfer PhD MD PDF

By Carl Eisdorfer PhD MD

ISBN-10: 0826130828

ISBN-13: 9780826130822

ISBN-10: 0826130984

ISBN-13: 9780826130983

New york 1982 Springer. 8vo, 436pp., index, unique gilt published hardcover. VG, tiny chip on entrance, no DJ.

Show description

Read Online or Download Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues PDF

Similar gerontology books

The Denial of Aging: Perpetual Youth, Eternal Life, and Other Dangerous Fantasies

Take heed to a quick interview with Dr. Muriel Gillick Host: Chris Gondek | manufacturer: Heron & Crane you have got argued politics along with your aunt on the grounds that highschool, yet failing eyesight now prevents her from retaining present with the newspaper. Your mom fractured her hip final 12 months and is restricted to a wheelchair.

Older Americans, Vital Communities: A Bold Vision for Societal Aging

This thought-provoking paintings grapples with the substantial variety of matters linked to the getting older inhabitants and demanding situations humans of every age to imagine extra boldly and extra creatively concerning the dating among older american citizens and their groups. W. Andrew Achenbaum starts by way of exploring the demographics of our getting older society and its impression on employment and markets, schooling, health and wellbeing care, faith, and political motion.

Genetics and Evolution of Aging

Getting older is a type of matters that many biologists think is essentially unknown. for this reason, they generally consider cozy delivering super facile generalizations which are both unsupported or at once refuted within the experimental literature. regardless of this unlucky precedent, getting older is a truly vast phenomenon that calls out for integration past the mere accumulating jointly of effects from disparate laboratory organisms.

Aging And Ethics: Philosophical Problems in Gerontology

The getting older Self and the getting older Society moral concerns concerning the aged have lately come to the fore. this could come as no shock: because the flip of the century, there was an eightfold in­ crease within the variety of americans over the age of sixty­ 5, and nearly a tripling in their share to the overall inhabitants.

Additional resources for Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues

Sample text

This resistance to tolerance induction was shown, by cell transfer studies, to be an intrinsic property of the peripheral B-cell population of older mice. The detailed mechanism for the age-related decrease in the ease of B-cell tolerance induction is not known. , 1972; DeKruyff and Siskind, 1980; Szewczuk and Siskind, 1977). The reduced affinity of the B-cell population of aged mice may thus contribute to the lack of susceptibility to tolerance induction. A defect in the capping of the surface immunoglobulin of B cells from aged rats following treatment with anti-immunoglobulin antibody has been reported (Woda and Feldman, 1979).

The major enzymatic step is the oxidation of ethanol to acetaldehyde by liver alcohol dehydrogenase (ADH). Smith et al. (1973) described multiple bands of ADH on starch gel electrophorcsis, attributed to three ADH gene loci in the liver. 8. This difference now has been correlated with electrophoretic variation at the ADH-2 locus. , 1975). Harada et al. (1980) have confirmed and extended these findings on ADH and shown, in addition, that 52 percent of Japanese have an unusual pattern of aldehyde dehydrogenase isozymes, with lower activity in metabolizing the highly potent acetaldehyde, which may well mediate certain intoxicating and toxic effects of ethanol.

Animal Studies Animal data must be interpreted with some caution. One cannot assume that other species metabolize drugs with the same pathway as does man; many exceptions have been reported (Omenn, 1976). Nevertheless, strain differences and species differences in the metabolism of specific drugs may provide useful models for the enzymatic steps involved and for correlation of metabolic degradation rates with therapeutic and adverse physiological or behavioral effects. Animal strains with markedly different longevity or different patterns of age-related diseases (Storer, 1966; Omenn, 1980) may be useful in seeking models for pharmacogenetic and pharmacokinetic aspects of aging.

Download PDF sample

Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues by Carl Eisdorfer PhD MD


by Steven
4.2

Rated 4.72 of 5 – based on 39 votes