By Edited by Brahim Attaf
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Extra resources for Advances in Composite Materials for Medicine and Nanotechnology
Biomaterials 25(24):5481-5489. , Shinomiya, K. and Tanaka, J. 2007. Fabrication of three-dimensional porous hydroxyapatite/collagen composite with rubber-like elasticity. Journal of Biomaterial Science, Polymer Edition 18(4):393-409. , Shinomiya, K. and Tanaka, J. 2006. Control of pore structure and mechanical property in hydroxyapatite/collagen composite using unidirectional ice growth. Materials Letters 60(8):999-1002. Zhang, J. and Misra, R. D. K. 2007. Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: Core-shell nanoparticle carrier and drug release response.
28 Advances in Composite Materials for Medicine and Nanotechnology The shape of the mineral phase of the composite material obtained by in vitro coprecipitation in the presence of fluoride is biomimetic and similar to the mineral phase of natural bone. The main difference between the mineral phases of bone and composite materials obtained in the presence of F- is the size of the crystal. In order to obtain naturalsized crystals in the mineral phase, crystallization inhibitors may be used. Under these conditions, we expect to reduce the size of the crystals.
HA, the mineral that occurs naturally in bone tissue, has also been used extensively as a tissue engineering scaffold material due to its 38 Advances in Composite Materials for Medicine and Nanotechnology osteoinductivity. It is typically used for coating biomedical implants to induce bone regeneration, allowing the implant to integrate with the surrounding tissue. While HA was originally popular for use as a scaffold for tissue engineering, it is non-resorbable in bulk form which has limited its popularity as a bone graft substitute material (Figure 3).
Advances in Composite Materials for Medicine and Nanotechnology by Edited by Brahim Attaf